Grim data highlighted the struggle for authorities around the world to bring the coronavirus pandemic under control Saturday, as the US reported 80,000 infections in a single day, France extended a curfew to two-thirds of citizens and Germany’s death toll passed 10,000.The World Health Organization had earlier warned of an “exponential” rise in infections threatening health systems’ ability to cope. But populations weary of social isolation and economic hardship have pushed back against fresh restrictions to slow the resurgent virus’ spread, including overnight clashes in hard-hit Naples between Italian police and hundreds of protesters. WHO chief Tedros Adhanom Ghebreyesus had on Friday warned that “too many countries are seeing an exponential increase in Covid-19 cases and that is now leading to hospitals and intensive care units running close to or above capacity — and we’re still only in October. We urge leaders to take immediate action to prevent further unnecessary deaths.” That message was echoed by the European Centre for Disease Prevention and Control (ECDC), whose director Andrea Ammon warned of a “highly concerning epidemiological situation”. Work has continued on the international quest to find a vaccine for the disease, with clinical trials for one candidate developed by AstraZeneca and Oxford University resuming in the United States on Friday, six weeks after a test subject became ill.